产品货号：
Z27302
中文名称：
SOX2抗体
英文名称：
Anti-SOX2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SOX2 Antibody |
| 指标别名 | ANOP3;MCOPS3;SOX2;Transcription factor SOX 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IHC,IF |
| 基因名称 | SOX2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SOX2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SOX.The immunogen is located within the first 50 amino acids of SOX2. |
| 计算分子量 | 34kDa |
| 成分 | SOX2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SOX2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate.SOX2 is required for stem-cell maintenance in the central nervous system,and also regulates gene expression in the stomach.Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia,a severe form of structural eye malformation.The role of SOX2 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of degenerative diseases.Artificial stem cells,termed induced pluripotent stem (iPS) cells,can be created by expressing SOX2 and the transcription factors POU5F1,Klf4 and Lin28 along with c-Myc in mouse fibroblasts.Other experiments have shown that iPS cells could be generated using expression plasmids expressing POU5F1,SOX2,KlfF4 and c-Myc,eliminating the need for virus introduction. |
| Uniprot ID | P48431 |
| 基因名全称 | SRY (sex determining region Y)-box 2 |
| 蛋白名全称 | SRY (sex determining region Y)-box 2 |
| 推荐稀释比 | SOX2 antibody can be used for detection of SOX2 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL and immunocytochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in mouse samples;Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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